Vaginal cancer is a rare type of cancer that starts in the vagina. The vagina is the canal leading from your cervix (the opening of your uterus) to the outside of your body.

You are more likely to develop vaginal cancer if:

• You're age 60 or older.
• You've had certain types of human papillomavirus (HPV) infections.
• You were exposed to a medicine called DES (diethylstilbestrol) before you were born. Between 1940-1971, DES was sometimes prescribed to prevent miscarriages. DES was later linked to different health problems, including vaginal cancer.
• You have had abnormal cells in your vagina, cervix, or uterus.

Vaginal cancer often doesn't have early symptoms. However, see your health care provider if you notice:

• Vaginal bleeding that is not your period
• A vaginal lump
• Pelvic pain
• Pain during sex
• Pain while urinating (peeing)
• Constipation or blood in your stool (poop) or urine (pee)

To find out if you have vaginal cancer, your provider will use tests that examine the vagina and other organs in your pelvis. These tests may include:

• A pelvic exam. Your provider may also do a Pap test and/or an HPV test during your pelvic exam.
• Colposcopy, a procedure to examine your cervix, vagina, and vulva.
• Biopsy, a procedure to remove some cells so they can be checked for cancer.

Vaginal cancer can often be cured if it is found early. Treatments for vaginal cancer may include surgery, radiation therapy, and/or chemotherapy.

Vaccines that protect against HPV infection may reduce your risk of vaginal cancer. The vaccines provide the most protection if you get them before you are exposed to HPV. So it's best to get vaccinated before you become sexually active.

NIH: National Cancer Institute

Vulvar cancer is a rare type of cancer. It forms in a woman's external genitals, called the vulva. The cancer usually grows slowly over several years. First, precancerous cells grow on vulvar skin. This is called vulvar intraepithelial neoplasia (VIN), or dysplasia. Not all VIN cases turn into cancer, but it is best to treat it early.

Often, vulvar cancer doesn't cause symptoms at first. However, see your doctor for testing if you notice:

• A lump in the vulva
• Vulvar itching or tenderness
• Bleeding that is not your period
• Changes in the vulvar skin, such as color changes or growths that look like a wart or ulcer

You are at greater risk if you've had a human papillomavirus (HPV) infection or have a history of genital warts. Your health care provider diagnoses vulvar cancer with a physical exam and a biopsy. Treatment varies, depending on your overall health and how advanced the cancer is. It might include surgery, radiation therapy, chemotherapy, or biologic therapy. Biologic therapy boosts your body's own ability to fight cancer.

NIH: National Cancer Institute

Tumors are abnormal growths in your body. They can be either benign or malignant. Benign tumors aren't cancer. Malignant ones are. Benign tumors grow only in one place. They cannot spread or invade other parts of your body. Even so, they can be dangerous if they press on vital organs, such as your brain.

Tumors are made up of extra cells. Normally, cells grow and divide to form new cells as your body needs them. When cells grow old, they die, and new cells take their place. Sometimes, this process goes wrong. New cells form when your body does not need them, and old cells do not die when they should. These extra cells can divide without stopping and may form a tumor.

Treatment often involves surgery. Benign tumors usually don't grow back.

NIH: National Cancer Institute

The urethra is the tube that allows urine to pass out of the body. In men, it's a long tube that runs through the penis. It also carries semen in men. In women, it's short and is just above the vagina. Urethral problems may happen due to aging, illness, or injury. They include:

• Urethral cancer - a rare cancer that happens more often in men
• Urethral stricture - a narrowing of the opening of the urethra
• Urethritis - inflammation of the urethra, sometimes caused by infection

Urethral problems may cause pain or difficulty passing urine. You may also have bleeding or discharge from the urethra.

Doctors diagnose urethral problems using different tests. These include urine tests, x-rays and an examination of the urethra with a scope called a cystoscope. Treatment depends on the cause of the problem. It may include medicines and, in severe cases, surgery.

Your kidneys make urine by filtering wastes and extra water from your blood. The urine travels from the kidneys to the bladder in two thin tubes called ureters.

The ureters are about 8 to 10 inches long. Muscles in the ureter walls tighten and relax to force urine down and away from the kidneys. Small amounts of urine flow from the ureters into the bladder about every 10 to 15 seconds.

Sometimes the ureters can become blocked or injured. This can block the flow of urine to the bladder. If urine stands still or backs up the ureter, you may get a urinary tract infection.

Doctors diagnose problems with the ureters using different tests. These include urine tests, x-rays, and examination of the ureter with a scope called a cystoscope. Treatment depends on the cause of the problem. It may include medicines and, in severe cases, surgery.

NIH: National Institute of Diabetes and Digestive and Kidney Diseases